Endosomal trafficking and protein sorting constitute fundamental processes that govern the intracellular localisation and recycling of membrane proteins in eukaryotic cells. Endosomes act as central ...
The capability to sort single cells of interest and to deeply characterize them has greatly added to our understanding of biology and disease states. Indeed, cell sorting has become an indispensable ...
The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs. An international research team led by the University of Bonn has made significant findings ...
Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer needed. The cellular waste disposal system called the proteasome is best ...
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Ageing slows brain protein clearance and shifts synaptic waste to microglia
By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all ...
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