In the annals of napkin illustration, continuous drug tablet manufacturing may have only one entry: Fernando Muzzio’s 2003 depiction of a tableting line for Janet Woodcock, then head of the US Food ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

In the manufacture of biotherapeutic drugs, the goal is to maximize production while minimizing costs, even though achieving this goal may involve a difficult transition—specifically, a transition ...

A photo of technicians working in front of a process train. Novartis's continuous manufacturing center in Basel, Switzerland, replicates an end-to-end manufacturing process developed at the ...

A lifecycle approach can be used to develop GMP-compliant cleaning procedures for continuous manufacturing of solid-dosage pharmaceuticals. It is now possible, as demonstrated by Janssen (1), for drug ...

Process Engineering encompasses the analysis, modeling, simulation, optimization, design, control and operation of process systems, from micro-sized systems to huge industrial facilities. Many ...

Rutgers engineers constructed a direct compaction line in collaboration with Janssen. Researchers in the Engineering Research Center for Structured Organic Particulate Systems (C-SOPS) at Rutgers, the ...