Medscape

Association Between Changes in Lumbar Modic Changes and Low Back Symptoms Over a Two-year Period

Background The association of Modic changes (MC) with low back pain (LBP) is unclear. The purpose of our study was to investigate the associations between the extent of Type 1 (M1) and Type 2 (M2) MC ...
manilatimes

Persica Pharmaceuticals' Positive Clinical Data for PP353 Treatment of Chronic Low Back Pain Published in The Lancet's eClinicalMedicine

London, UK, 3 February 2026 - Persica Pharmaceuticals Limited (Persica), a clinical stage biotechnology company developing a transformative treatment for chronic Low Back Pain (cLBP), today announces ...
EurekAlert!

Modic changes linked to microbial differences in lumbar spine

August 20, 2024 — Among patients undergoing lumbar spinal fusion, the presence of Modic changes is associated with differences in microbial diversity and metabolites in the lumbar cartilaginous ...
Medscape

Association Between Changes in Lumbar Modic Changes and Low Back Symptoms Over a Two-year Period

In this 2-year follow-up study, we found a significant positive association between the change in the extent of M1 and change in ODI. We also found a positive association between the change in the ...
Yahoo Finance

Persica Pharmaceuticals' Positive Clinical Data for PP353 Treatment of Chronic Low Back Pain Published in The Lancet's eClinicalMedicine

Trial demonstrated that PP353 delivers clinically meaningful and durable reduction in pain and disability in patients with chronic Low Back Pain and Modic Type 1 changes PP353 has the potential to ...