In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

PET imaging of reactive astrocyte-neuron interaction reveals new insights into Alzheimer's disease pathology, offering a potential breakthrough in diagnosis and treatment Recently, a team of South ...

Once overlooked, astrocytes are increasingly recognized as star players in Alzheimer’s disease, with recent studies blaming them for feeding into a neurotoxic stew that kills neurons. In the September ...

Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...

When the brain is injured in some way, a wide range of biochemical changes are triggered that can affect crucial brain cells known as astrocytes. They are a type of glial cell, and brain injuries ...

As neuronal supporters and immune surveyors, astrocytes and microglia are no mere bystanders to the neuronal mayhem that unfolds in Alzheimer’s disease. At the AD/PD meeting, held March 5-9 in Lisbon, ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

Researchers have discovered the mechanism by which a cluster of astrocytes, specialized brain cells, in the hypothalamus cause obesity in mice. Their study also identified a drug that inhibited the ...

When we learn a new motor skill—whether mastering a piano passage or refining balance while walking—the brain must reorganize the circuits that control movement. For decades, this process of synaptic ...

The selective MAOB inhibitor KDS2010 significantly improved functional recovery in a spinal cord injury animal model. Treated animals showed marked restoration of behavioral scores and locomotor ...