The axon initial segment (AIS) functions as both a structural and a functional bridge between neuronal input and output. The AIS is characterized by clustered voltage-gated Na + and K + channels that ...

While mutated C9ORF72 leads to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD), scientists still wonder what the healthy protein does. In the October 10 Nature ...

In the developing nervous system, extensive migrations of neurons and axon growth cones occur largely along the natural body axes and pattern axonal networks to establish functional connectivity.