A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D.
DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...
Complete the form below to access this guide to sequencing epigenetic modifications. Epigenetics is the study of chemical ...
DNA Methylation: Timekeeper of Biological Age from thescientistllc on Vimeo. Cellular senescence, telomere shortening, and changes in gene expression have been well documented to contribute to the ...
All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...
DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...
Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...
"We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that are based on methylation levels of individual ...
DNA methylation profiles in whole blood samples from 77 patients with CN-AML in The Cancer Genome Atlas (LAML cohort) were analyzed. Individual 5’-cytosine-phosphate-guanine-3’ (CpG) sites were ...
A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 12, 2025, titled "DNA methylation entropy is a biomarker for aging." Researchers Jonathan Chan, Liudmilla Rubbi, and ...
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